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. 2018 Aug 13;10(8):425.
doi: 10.3390/v10080425.

Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases

Romy Conzade  1   2 , Rebecca Grant  3   4 , Mamunur Rahman Malik  5 , Amgad Elkholy  6 , Mohamed Elhakim  7 , Dalia Samhouri  8 , Peter K Ben Embarek  9 , Maria D Van Kerkhove  10
Affiliations

Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases

Romy Conzade et al. Viruses. .

Abstract

Dromedary camels (Camelus dromedarius) are now known to be the vertebrate animal reservoir that intermittently transmits the Middle East respiratory syndrome coronavirus (MERS-CoV) to humans. Yet, details as to the specific mechanism(s) of zoonotic transmission from dromedaries to humans remain unclear. The aim of this study was to describe direct and indirect contact with dromedaries among all cases, and then separately for primary, non-primary, and unclassified cases of laboratory-confirmed MERS-CoV reported to the World Health Organization (WHO) between 1 January 2015 and 13 April 2018. We present any reported dromedary contact: direct, indirect, and type of indirect contact. Of all 1125 laboratory-confirmed MERS-CoV cases reported to WHO during the time period, there were 348 (30.9%) primary cases, 455 (40.4%) non-primary cases, and 322 (28.6%) unclassified cases. Among primary cases, 191 (54.9%) reported contact with dromedaries: 164 (47.1%) reported direct contact, 155 (44.5%) reported indirect contact. Five (1.1%) non-primary cases also reported contact with dromedaries. Overall, unpasteurized milk was the most frequent type of dromedary product consumed. Among cases for whom exposure was systematically collected and reported to WHO, contact with dromedaries or dromedary products has played an important role in zoonotic transmission.

Keywords: MERS-CoV; dromedary camels; zoonotic transmission.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Zaki A.M., van Boheemen S., Bestebroer T.M., Osterhaus A.D., Fouchier R.A. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N. Engl. J. Med. 2012;367:1814–1820. doi: 10.1056/NEJMoa1211721. - DOI - PubMed
    1. WHO WHO MERS-CoV Global Summary and Assessment of risk. [(accessed on 30 July 2018)];2017 Jul 21; Available online: http://www.who.int/emergencies/mers-cov/risk-assessment-july-2017.pdf?ua=1.
    1. Arwady M.A., Alraddadi B., Basler C., Azhar E.I., Abuelzein E., Sindy A.I., Sadiq B.M., Althaqafi A.O., Shabouni O., Banjar A., et al. Middle East Respiratory Syndrome Coronavirus Transmission in Extended Family, Saudi Arabia, 2014. Emerg. Infect. Dis. 2016;22:1395–1402. doi: 10.3201/eid2208.152015. - DOI - PMC - PubMed
    1. Hijawi B., Abdallat M., Sayaydeh A., Alqasrawi S., Haddadin A., Jaarour N., Alsheikh S., Alsanouri T. Novel coronavirus infections in Jordan, April 2012: Epidemiological findings from a retrospective investigation. East. Mediterr. Health J. 2013;19(Suppl. 1):S12–S18. doi: 10.26719/2013.19.supp1.S12. - DOI - PubMed
    1. Assiri A., McGeer A., Perl T.M., Price C.S., Al Rabeeah A.A., Cummings D.A., Alabdullatif Z.N., Assad M., Almulhim A., Makhdoom H., et al. Hospital outbreak of Middle East respiratory syndrome coronavirus. N. Engl. J. Med. 2013;369:407–416. doi: 10.1056/NEJMoa1306742. - DOI - PMC - PubMed

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