Inherited complement component abnormalities
- PMID: 3010807
- DOI: 10.1146/annurev.me.37.020186.002001
Inherited complement component abnormalities
Abstract
Inherited deficiencies of early complement components are frequently associated with immune/rheumatic disorders and recurrent (Neisserial) infection with deficiency of late complement components. The genetic complexity of complement components is further demonstrated by electrophoretic allotypy and analysis of DNA restriction fragment length polymorphisms.
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