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. 2018 Jul-Sep;7(3):183-187.
doi: 10.4103/sajc.sajc_15_18.

The epidemiology, treatment, and determinants of outcome of primary head and neck cancers at the Jos University Teaching Hospital

Adeyi A Adoga  1 , Daniel D Kokong  1 , Nuhu D Ma'an  1 , Olugbenga A Silas  2 , Ayuba M Dauda  2 , John P Yaro  1 , Joyce G Mugu  1 , Chukwunonso J Mgbachi  1 , Caleb J Yabak  1
Affiliations

The epidemiology, treatment, and determinants of outcome of primary head and neck cancers at the Jos University Teaching Hospital

Adeyi A Adoga et al. South Asian J Cancer. 2018 Jul-Sep.

Abstract

Introduction: This study aims to evaluate the epidemiology, treatment, and factors that determine the outcomes of head and neck cancers (HNC).

Patients and methods: Retrospective analytical review of HNC managed at the Jos University Teaching Hospital between May 2007 and April 2017 using the International Classification of Diseases version 10.

Results: Of 487 head and neck neoplasms, 129 (26.5%) were malignant and 122 health records met the criteria for analysis consisting of 83 (68.0%) males and 39 (32.0%) females aged 13 years to 85 years (mean = 51 years; standard deviation = ±16.0 years). The most common presenting feature was nasal obstruction (n = 47; 38.5%). The most common tumor site was the nasopharynx (n = 34; 27.9%). Mean duration of symptoms was 13.3 months. Alcohol (P = 0.02), cigarette smoking (P = 0.01), and cooking wood smoke (P = 0.01) were associated with advanced tumor stage. Squamous cell carcinoma was the most common histological type. Posttreatment complication rate was 47.5%. Lost to follow-up rate was 55.7%. The lungs were the most common distant metastatic site. The case fatality rate was 18.0%.

Conclusion: HNC constitutes almost a quarter of head and neck tumors affecting twice the number of males in their sixth decade with nasopharyngeal cancers being the most common in both genders. Several modifiable variables are noted to target appropriate future cancer education for lifestyle modification, screening for early detection and treatment.

Keywords: Determinants; Jos-Nigeria; epidemiology; head and neck cancer; outcomes.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Stage of disease at presentation
Figure 2
Figure 2
Distribution of histological type
See this image and copyright information in PMC

References

    1. Emadzadeh M, Shahidsales S, Mohammadian Bajgiran A, Salehi M, Massoudi T, Nikfarjam Z, et al. Head and neck cancers in North-East Iran: A 25 year survey. Iran J Otorhinolaryngol. 2017;29:137–45. - PMC - PubMed
    1. Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Allen C, Barber RM, Barregard L, Bhutta ZA, et al. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: A Systematic analysis for the global burden of disease study. JAMA Oncol. 2017;3:524–48. - PMC - PubMed
    1. Pezzuto F, Buonaguro L, Caponigro F, Ionna F, Starita N, Annunziata C, et al. Update on head and neck cancer: Current knowledge on epidemiology, risk factors, molecular features and novel therapies. Oncology. 2015;89:125–36. - PubMed
    1. Adisa AO, Adeyemi BF, Oluwasola AO, Kolude B, Akang EE, Lawoyin JO. Clinicopathological profile of head and neck malignancies at university college hospital, Ibadan, Nigeria. Head Face Med. 2011;7:9. - PMC - PubMed
    1. Patel SG, Shah JP. TNM staging of cancers of the head and neck: Striving for uniformity among diversity. CA Cancer J Clin. 2005;55:242–58. - PubMed