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Meta-Analysis
. 2018 Nov;31(6):445-455.
doi: 10.1097/YCO.0000000000000453.

Relapse in anorexia nervosa: a systematic review and meta-analysis

Tamara Berends  1 , Nynke Boonstra  2 , Annemarie van Elburg  1   3   4
Affiliations
Meta-Analysis

Relapse in anorexia nervosa: a systematic review and meta-analysis

Tamara Berends et al. Curr Opin Psychiatry. 2018 Nov.

Abstract

Purpose of review: Relapse is common in patients with anorexia nervosa. The aim of this study is to systematically review the existing literature on relapse in anorexia nervosa.

Recent findings: A systematic literature search was conducted in PubMed, PsychInfo and CINAHL published up to April 2018. Of the 1527 studies screened, 16 studies were included in the present review.

Summary: This analysis shows that, of the patients included in this review, 31% relapsed after treatment. The highest risk of relapse is during the first year after discharge and this risk continues for up to 2 years. An overview was made of all factors significantly associated with a higher risk of relapse, resulting in the following four clusters: eating disorder variables, comorbidity symptoms, process treatment variables and demographic variables. Future research on relapse prevention is necessary to further unravel the mechanisms that might lead to relapse.

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