Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986;41(2-3):305-10.
doi: 10.1016/0378-1119(86)90111-3.

Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens

M Emi, Y Nakamura, M Ogawa, T Yamamoto, T Nishide, T Mori, K Matsubara

Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens

M Emi et al. Gene. 1986.

Abstract

Two cDNA clones encoding two major human trypsinogen isozymes were isolated from a human pancreatic cDNA library. The deduced amino acid (aa) sequences of the two trypsinogen precursors are found to have 89% sequence homology, and have the same number of aa (247), including 15 aa for a signal peptide and 8 aa for an activation peptide. Southern blot analysis of human genomic DNA using the cloned cDNA as a probe, revealed that the human trypsinogen genes constitute a multigene family of more than ten genes.

PubMed Disclaimer

Associated data

LinkOut - more resources