doi: 10.1007/BF00292658.
Characteristics and distribution of beta thalassemia haplotypes in South China
- PMID: 3011644
- DOI: 10.1007/BF00292658
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Characteristics and distribution of beta thalassemia haplotypes in South China
Hum Genet.
1986 May.
Abstract
Eleven restriction site polymorphisms in the beta-globin gene cluster were determined in 48 Chinese with homozygous beta-thalassemia and their parents. Seven haplotypes were identified as associated with the beta thal chromosome and 25 with the beta A chromosome. The distribution of the various beta thal haplotypes in different regions of South China was mapped and discussed in relation to prenatal diagnosis and migration of the Chinese people.
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