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. 1986 May;73(1):23-6.
doi: 10.1007/BF00292658.

Characteristics and distribution of beta thalassemia haplotypes in South China

V Chan, T K Chan, M Y Cheng, N K Leung, Y W Kan, D Todd

Characteristics and distribution of beta thalassemia haplotypes in South China

V Chan et al. Hum Genet. 1986 May.

Abstract

Eleven restriction site polymorphisms in the beta-globin gene cluster were determined in 48 Chinese with homozygous beta-thalassemia and their parents. Seven haplotypes were identified as associated with the beta thal chromosome and 25 with the beta A chromosome. The distribution of the various beta thal haplotypes in different regions of South China was mapped and discussed in relation to prenatal diagnosis and migration of the Chinese people.

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References

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