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Review
. 2018 Jul;10(Suppl 19):S2248-S2259.
doi: 10.21037/jtd.2018.03.169.

Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies

Affiliations
Review

Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies

Zhengtu Li et al. J Thorac Dis. 2018 Jul.

Abstract

The direct replication of influenza virus is not the only cause of harm to human health; influenza infection leading to a hyper-inflammatory immune response can also result in serious conditions. So, the treatment strategy for influenza needs to keep balance between antivirus and anti-inflammation. Herein, we review the treatment strategies of anti-influenza drugs and traditional Chinese medicines.

Keywords: Influenza; anti-inflammation; antivirus; chemical drug; traditional Chinese medicine.

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

References

    1. Yang P, Deng Y, Pang X, et al. Severe, critical and fatal cases of 2009 H1N1 influenza in China. J Infect 2010;61:277-83. 10.1016/j.jinf.2010.07.010 - DOI - PubMed
    1. Qu JX, Gu L, Pu ZH, et al. Viral etiology of community-acquired pneumonia among adolescents and adults with mild or moderate severity and its relation to age and severity. BMC Infect Dis 2015;15:89. 10.1186/s12879-015-0808-0 - DOI - PMC - PubMed
    1. Peiris JS, Hui KP, Yen HL. Host response to influenza virus: protection versus immunopathology. Curr Opin Immunol 2010;22:475-81. 10.1016/j.coi.2010.06.003 - DOI - PMC - PubMed
    1. Peiris JS, Cheung CY, Leung CY, et al. Innate immune responses to influenza A H5N1: friend or foe? Trends Immunol 2009;30:574-84. 10.1016/j.it.2009.09.004 - DOI - PMC - PubMed
    1. Oakley OR, Garvy BA, Humphreys S, et al. Increased weight loss with reduced viral replication in interleukin-10 knock-out mice infected with murine cytomegalovirus. Clin Exp Immunol 2008;151:155-64. 10.1111/j.1365-2249.2007.03533.x - DOI - PMC - PubMed