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. 2017 May 31:2017:9805145.
doi: 10.1155/2017/9805145. eCollection 2017.

Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon

Carl-Joe Mehanna  1 , Maamoun Abdul Fattah  1 , Hani Tamim  2 , Mona P Nasrallah  3 , Raya Zreik  3 , Sandra S Haddad  4 , Jaafar El-Annan  5 , Samih Raad  6 , Randa S Haddad  1 , Haytham I S Salti  1
Affiliations

Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon

Carl-Joe Mehanna et al. J Ophthalmol. .

Erratum in

Abstract

Objective: To estimate the 5-year incidence of progression rate and regression rate and risk factors for diabetic retinopathy (DR) in a cohort of Lebanese patients with type II diabetes.

Methods: We followed a cohort of 462 Lebanese patients with type II diabetes for over 5 years at the American University of Beirut Medical Center. Patients underwent yearly complete ophthalmic evaluation and fundus photographs and were assessed for the incidence, stage, and evolution of DR using modified Airlie House classification.

Results: Among the 462 patients, 281 had no DR at baseline. The 5-year cumulative incidence of any DR was 10% (95% CI: 6-13), and only baseline microalbuminuria correlated with the development of DR (OR = 10.53, 95% CI: 4.39-25.23, p < 0.0001). Among the 181 patients with baseline DR, the worsening and regression rates of DR were 31.5% (95% CI: 25-38) and 9% (95% CI: 5-13), respectively. Microalbuminuria also approached statistical significance as a risk factor for DR worsening (OR = 1.89, 95% CI: 0.97-3.70, p = 0.06).

Conclusion: The 5-year incidence of DR in this hospital-based cohort is relatively low. Microalbuminuria was independently associated with the incidence and progression of the disease. We recommend to screen patients with type II diabetes for microalbuminuria as prognostic for the development and worsening of DR.

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References

    1. Congdon N., O’Colmain B., Klaver C. C., et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol (Chicago, Ill 1960) 2004;122(4):477–485. doi: 10.1001/archopht.122.4.477. - DOI - PubMed
    1. Younis N., Broadbent D. M., Vora J. P., Harding S. P., Liverpool Diabetic Eye Study Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool diabetic eye study: a cohort study. Lancet (London, England) 2003;361(9353):195–200. doi: 10.1016/S0140-6736(03)12267-2. - DOI - PubMed
    1. Stratton I. M., Kohner E. M., Aldington S. J., et al. UKPDS 50: risk factors for incidence and progression of retinopathy in type II diabetes over 6 years from diagnosis. Diabetologia. 2001;44(2):156–163. doi: 10.1007/s001250051594. - DOI - PubMed
    1. Xu J., Xu L., Wang Y. X., You Q. S., Jonas J. B., Wei W. B. Ten-year cumulative incidence of diabetic retinopathy. The Beijing Eye Study 2001/2011. PLoS One. 2014;9(10, article e111320) doi: 10.1371/journal.pone.0111320. - DOI - PMC - PubMed
    1. Klein R., Klein B. E., Moss S. E., Cruickshanks K. J. The Wisconsin epidemiologic study of diabetic retinopathy. XIV. Ten-year incidence and progression of diabetic retinopathy. Arch Ophthalmol (Chicago, Ill 1960) 1994;112(9):1217–1228. doi: 10.1016/S0161-6420(95)31052-4. - DOI - PubMed

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