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. 2018 Aug 16;25(8):929-930.
doi: 10.1016/j.chembiol.2018.08.002.

Dysregulating ClpP: From Antibiotics to Anticancer?

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Dysregulating ClpP: From Antibiotics to Anticancer?

David A Dougan et al. Cell Chem Biol. .
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Abstract

In this issue of Cell Chemical Biology, Wong et al. (2018) identify several dysregulators of a key mitochondrial protease: casein lytic protease P (ClpP). These dysregulators were found to trigger programmed cell death and may offer fresh avenues for the development of novel cancer therapeutics.

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