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. 2018 Aug 17;13(1):204.
doi: 10.1186/s13018-018-0912-0.

The effects of hyperlipidemia on rotator cuff diseases: a systematic review

Yang Yang  1 , Jin Qu  2
Affiliations

The effects of hyperlipidemia on rotator cuff diseases: a systematic review

Yang Yang et al. J Orthop Surg Res. .

Abstract

Background: Rotator cuff disease is a common condition that causes shoulder pain and functional disability. Recent studies suggested that hyperlipidemia might be associated with the development of rotator cuff disease. The objective of this study was to explore the relationship of hyperlipidemia and rotator cuff diseases.

Methods: A computerized search using relevant search terms was performed in the PubMed, EMBASE, and Cochrane Library databases, as well as a manual search of reference and citation lists of the included studies. Searches were limited to studies that explored the association of hyperlipidemia and rotator cuff diseases.

Results: Sixteen studies were included in this systematic review. Ten of sixteen included studies suggested an association between dyslipidemia and rotator cuff diseases, while the other six studies did not find an association. Two studies demonstrated there were an association between statins and reduced risk of developing rotator cuff diseases or decreased incidence of revision after rotator cuff repair.

Conclusion: The current study suggested that there was an association between hyperlipidemia and rotator cuff diseases. Furthermore, current evidence suggested that use of statins could decrease the risk of developing rotator cuff diseases and the incidence of revision after rotator cuff repair. Future high-quality studies are highly needed to confirm these findings.

Keywords: Hyperlipidemia; Rotator cuff diseases; Statins.

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Competing interests

The authors declare that they have no competing interests.

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Figures

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Fig. 1
The flow diagram illustrating the search process
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References

    1. Hermans J, Luime JJ, Meuffels DE, Reijman M, Simel DL, Bierma-Zeinstra SM. Does this patient with shoulder pain have rotator cuff disease?: the Rational Clinical Examination systematic review. JAMA. 2013;310:837–847. doi: 10.1001/jama.2013.276187. - DOI - PubMed
    1. Galatz LM, Ball CM, Teefey SA, Middleton WD, Yamaguchi K. The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears. J Bone Joint Surg Am. 2004;86-A:219–224. doi: 10.2106/00004623-200402000-00002. - DOI - PubMed
    1. Mall NA, Tanaka MJ, Choi LS, Paletta GA., Jr Factors affecting rotator cuff healing. J Bone Joint Surg Am. 2014;96:778–788. doi: 10.2106/JBJS.M.00583. - DOI - PubMed
    1. Chen YQ, Zhao SP, Zhao YH. Efficacy and tolerability of coenzyme A vs pantethine for the treatment of patients with hyperlipidemia: a randomized, double-blind, multicenter study. J Clin Lipidol. 2015;9:692–697. doi: 10.1016/j.jacl.2015.07.003. - DOI - PubMed
    1. Esenkaya I, Unay K. Tendon, tendon healing, hyperlipidemia and statins. Muscles Ligaments Tendons J. 2011;1:169–171. - PMC - PubMed

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