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Review
. 2018 Apr-Jun;21(2):107-115.
doi: 10.4103/aian.AIAN_33_18.

Evolving Landscape of Multiple Sclerosis in India: Challenges in the Management

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Review

Evolving Landscape of Multiple Sclerosis in India: Challenges in the Management

Sudhir Kumar et al. Ann Indian Acad Neurol. 2018 Apr-Jun.

Abstract

Multiple sclerosis (MS) is a chronic neurological disease which often leads to disability. The complex etiology and progressive nature pose challenges in the management of patients with MS, particularly in developing countries like India. Lack of data on prevalence further complicates estimation of the magnitude of MS in India. There are various other challenges associated with management of patients with MS due to which the therapy is utilized by only a small segment of population in India. This article encapsulates the gaps and challenges in the management of patients with MS and presents suggestions and recommendations of the members of advisory boards held to discuss these challenges. The advisory board members suggested that an early diagnosis of MS and an early initiation of treatment are essential to achieve better results for tackling MS-related challenges. In addition, awareness and education about MS among people, regular training to physicians, emphasis on the use of revised 2010 McDonald criteria, and utilization of advanced diagnostic modalities in magnetic resonance imaging would help to achieve desirable as well as effective therapeutic outcomes. Further, access to an easy-to-use therapy delivery system could also be beneficial in attaining an adequate treatment adherence and related health benefits.

Keywords: Adherence; challenges; diagnosis; multiple sclerosis; referral; treatment.

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Conflict of interest statement

The authors received honoraria as consultants for Merck Ltd, Mumbai, India, for these advisory board meetings. Dr. Harshal and Dr. Priti are employees of Merck Ltd., Mumbai, India, an affiliate of Merck KGaA (Darmstadt, Germany).[72]

Figures

Figure 1
Figure 1
McDonald Criteria (2010) for Diagnosis of Multiple Sclerosis
Figure 2
Figure 2
Assessment Parameters to Evaluate Effectiveness of Various Multiple Sclerosis Associated Therapeutic Options[395472]

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References

    1. Compston A, Coles A. Multiple sclerosis. Lancet. 2002;359:1221–31. - PubMed
    1. Dutta R, Trapp BD. Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis. Prog Neurobiol. 2011;93:1–2. - PMC - PubMed
    1. Jobin C, Larochelle C, Parpal H, Coyle PK, Duquette P. Gender issues in multiple sclerosis: An update. Womens Health (Lond) 2010;6:797–820. - PubMed
    1. Myhr KM. Diagnosis and treatment of multiple sclerosis. Acta Neurol Scand Suppl. 2008;188:12–21. - PubMed
    1. Bhatia R, Bali P, Chaudhari RM. Epidemiology and genetic aspects of multiple sclerosis in India. Ann Indian Acad Neurol. 2015;18:S6–S10. - PMC - PubMed