Correlations between T-cell specificity and the structure of the antigen receptor
- PMID: 3012351
- DOI: 10.1038/321219a0
Correlations between T-cell specificity and the structure of the antigen receptor
Abstract
The derived amino-acid sequences of the heterodimeric antigen receptors expressed by a series of murine T-cell clones are presented. A comparison of the receptor sequences indicates that several mechanisms for generating receptor diversity can influence T-cell specificity, including junctional diversity, combinatorial joining, and combinatorial chain associations.
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