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. 2018 Aug 20;16(1):94.
doi: 10.1186/s12915-018-0564-x.

Open questions: How many genes do we have?

Steven L Salzberg  1
Affiliations

Open questions: How many genes do we have?

Steven L Salzberg. BMC Biol. .

Abstract

Seventeen years after the initial publicationx of the human genome, we still haven't found all of our genes. The answer turns out to be more complex than anyone had imagined when the Human Genome Project began.

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Conflict of interest statement

Competing interests

The author declares that he has no competing interests.

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References

    1. Understanding our genetic inheritance: the U.S. Human Genome Project, the first five years 1990. https://www.genome.gov/10001477/human-genome-projects-fiveyear-plan-1991.... Accessed 20 July 2018.
    1. International Human Genome Sequencing Consortium Initial sequencing and analysis of the human genome. Nature. 2001;409(6822):860–921. doi: 10.1038/35057062. - DOI - PubMed
    1. Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, et al. The sequence of the human genome. Science. 2001;291(5507):1304–1351. doi: 10.1126/science.1058040. - DOI - PubMed
    1. International Human Genome Sequencing Consortium Finishing the euchromatic sequence of the human genome. Nature. 2004;431(7011):931–945. doi: 10.1038/nature03001. - DOI - PubMed
    1. Mortazavi A, Williams BA, McCue K, Schaeffer L, Wold B. Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods. 2008;5(7):621–628. doi: 10.1038/nmeth.1226. - DOI - PubMed

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