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. 1986 May 6;66(1):113-9.
doi: 10.1016/0304-3940(86)90175-8.

Collagenase digestion alters the organization and turnover of junctional acetylcholine receptors

R J Bloch, J H Steinbach, J P Merlie, S Heinemann

Collagenase digestion alters the organization and turnover of junctional acetylcholine receptors

R J Bloch et al. Neurosci Lett. .

Abstract

Acetylcholine receptors at the vertebrate neuromuscular junction are highly organized and metabolically very stable. We report here that digestion of adult rat skeletal muscle with collagenase disorganizes junctional receptors and increases their turnover rate.

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