Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1986 May 27;14(10):4281-92.
doi: 10.1093/nar/14.10.4281.

DNA sequence of the herpes simplex virus type 1 gene encoding glycoprotein gH, and identification of homologues in the genomes of varicella-zoster virus and Epstein-Barr virus

D J McGeoch, A J Davison
Free PMC article
Comparative Study

DNA sequence of the herpes simplex virus type 1 gene encoding glycoprotein gH, and identification of homologues in the genomes of varicella-zoster virus and Epstein-Barr virus

D J McGeoch et al. Nucleic Acids Res. .
Free PMC article

Abstract

We have determined the sequence of herpes simplex virus type 1 DNA around the previously mapped location of sequences encoding an epitope of glycoprotein gH, and have deduced the structure of the gH gene and the amino acid sequence of gH. The unprocessed polypeptide is predicted to contain 838 amino acids, and to possess an N-terminal signal sequence and a C-terminal transmembrane sequence. Temperature-sensitive mutant tsQ26 maps within the predicted gH coding sequence. Homologous genes were identified in the genomes of two other herpesviruses, namely varicella-zoster virus and Epstein-Barr virus.

PubMed Disclaimer

References

    1. Virus Res. 1985 Oct;3(3):271-86 - PubMed
    1. Nucleic Acids Res. 1985 Nov 25;13(22):8143-63 - PubMed
    1. J Virol. 1978 Nov;28(2):624-42 - PubMed
    1. Nucleic Acids Res. 1980 Dec 20;8(24):5949-64 - PubMed
    1. Proc Natl Acad Sci U S A. 1981 Mar;78(3):1441-5 - PubMed

Publication types

Substances

Associated data