Sepsis secondary to complicated skin and soft tissue infection caused by Ignatzschineria indica. First case report in Latin America

Abstract

Introduction: Ignatzschineria is a recently recognized genus associated with larvae infestation Members of this genus are pathogens infrequently implicated in human disease. During the last decade, fewer than 10 cases of infection with Ignatzchineria species have been reported around the world. Bacteria of the genera Ignatzchineria and Wohlfahrtiimonas have been isolated from larvae of the parasitic fly Wohlfahrtia magnifica, which is found in Europe, Asia and North Africa, and is associated with myiasis in several animal species, but rarely in humans.

Case presentation: We report the first case of sepsis associated with complicated skin and soft tissue infection caused by I. indica in Latin America.

Conclusion: The clinical and molecular findings in our report add information to the accumulating data on emerging pathogens of this type, their geographic distribution, the correlation between the emergence of infectious diseases and social and economic inequalities, as well as the effects of global climate changes on potentially unusual distribution of vectors. We consider that fly larvae should be regarded as a potential source of specific arthropod-borne bacterial systemic infections.

Keywords: 16S rRNA sequencing; Ignatzchineria; ciprofloxacin; clindamycin; maggots; sepsis.