Comparative Study
doi: 10.1128/AAC.29.3.524.
Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs
- PMID: 3013088
- PMCID: PMC180428
- DOI: 10.1128/AAC.29.3.524
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Comparative Study
Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs
Antimicrob Agents Chemother.
1986 Mar.
Abstract
The susceptibilities of varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) to 17 nucleoside analogs were compared by a plaque reduction assay with human embryonic lung fibroblast cells. The susceptibility of VZV to certain nucleoside analogs was different from that of HSV-1. Against VZV the 5-halogenovinyl-arabinosyluracils were the most potent of the compounds tested.
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