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Comment
. 2018 Oct;43(10):747-748.
doi: 10.1016/j.tibs.2018.08.004. Epub 2018 Aug 18.

Ki-67: More Hidden behind a 'Classic Proliferation Marker'

Raquel Sales Gil  1 , Paola Vagnarelli  2
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Ki-67: More Hidden behind a 'Classic Proliferation Marker'

Raquel Sales Gil et al. Trends Biochem Sci. 2018 Oct.

Abstract

Nuclear antigen Ki-67 is widely accepted as a cell proliferation marker in both research and cancer diagnostic settings. Despite its extensive use and clinical value, very little is still known about the biological function of Ki-67. A recent work published in Cell Reports has revealed important novel aspects of Ki-67 regulation that could provide new and extended prognostic and therapeutic value.

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