Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1977 May;66(3):273-7.
doi: 10.1111/j.1651-2227.1977.tb07893.x.

Factor XIII (fibrin stabilising factor) in Henoch-Schönlein's purpura

P Henriksson, U Hedner, I M Nilsson
Case Reports

Factor XIII (fibrin stabilising factor) in Henoch-Schönlein's purpura

P Henriksson et al. Acta Paediatr Scand. 1977 May.

Abstract

In 13 out of 17 consecutive children with Henoch-Schönlein's purpura the factor XIII determined with the dansyl cadaverine method was found to be decreased during the acute phase. The decrease is assumed to be due to a specific degradation by proteolytic enzymes liberated from inflammatory cells, with defective local haemostasis as a result. This assumption is strengthened by the observation that treatment with factor XIII combined with an antifibrinolytic drug controlled life-threatening gastro-intestinal bleeding in one of the patients. It would therefore appear that such treatment might offer a new possibility of controlling severe haemorrhages in Henoch-Schönlein's purpura.

PubMed Disclaimer

Publication types