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Comment
. 2018 Aug 21;49(2):208-210.
doi: 10.1016/j.immuni.2018.08.009.

Dangerously Fit: Extracellular ATP Aids Memory T Cell Metabolism

Trever T Greene  1 , Lara Labarta-Bajo  1 , Elina I Zuñiga  2
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Dangerously Fit: Extracellular ATP Aids Memory T Cell Metabolism

Trever T Greene et al. Immunity. .
Free article

Abstract

In a recent issue of Nature, Borges da Silva et al. (2018) reveal that P2RX7, a receptor for extracellular ATP, promotes CD8 T cell memory by enhancing metabolic fitness. This work links an ancient "danger" signal with long-term immunity.

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