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Review
. 2018 Aug 21;19(9):2471.
doi: 10.3390/ijms19092471.

Advances in Imaging Specific Mediators of Inflammatory Bowel Disease

Nicole Dmochowska  1 , Hannah R Wardill  2 , Patrick A Hughes  3
Affiliations
Review

Advances in Imaging Specific Mediators of Inflammatory Bowel Disease

Nicole Dmochowska et al. Int J Mol Sci. .

Abstract

Inflammatory bowel disease (IBD) is characterized by chronic remitting and relapsing inflammation of the lower gastrointestinal tract. The etiology underlying IBD remains unknown, but it is thought to involve a hypersensitive immune response to environmental antigens, including the microbiota. Diagnosis and monitoring of IBD is heavily reliant on endoscopy, which is invasive and does not provide information regarding specific mediators. This review describes recent developments in imaging of IBD with a focus on positron emission tomography (PET) and single-photon emission computed tomography (SPECT) of inflammatory mediators, and how these developments may be applied to the microbiota.

Keywords: Inflammatory Bowel Disease (IBD), colitis; PET; SPECT; chemokine; cytokine; inflammation; microbiota.

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Conflict of interest statement

The authors declare no conflict of interest.

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