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. 2019 Feb 13;17(7):1709-1713.
doi: 10.1039/c8ob01806e.

Palladium-catalyzed salt-free double decarboxylative aryl allylation

Ryan A Daley  1 , Joseph J Topczewski
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Palladium-catalyzed salt-free double decarboxylative aryl allylation

Ryan A Daley et al. Org Biomol Chem. .

Abstract

This report describes a palladium-catalyzed decarboxylative aryl allylation between unactivated benzoic acids and allylic carbonates. This transformation successfully couples a variety of carbonates and benzoic acids in good yield (up to 94%) using 1 mol% palladium. This salt free allyl-arylation proceeds without added base, copper, or silver. The only stoichiometric byproducts are carbon dioxide and tert-butanol.

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