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. 1977 Apr-Jun;128C(3):699-708.

Affinity chromatographic analysis of murine interferons induced by viruses and by T and B cell stimulants

  • PMID: 301376

Affinity chromatographic analysis of murine interferons induced by viruses and by T and B cell stimulants

J Wietzerbin et al. Ann Immunol (Paris). 1977 Apr-Jun.

Abstract

Murine interferons induced by viruses and by non-viral substances such as lectins, tilorone, lipopolysaccharide and Brucella have been analysed by affinity chromatography on a column of Sepharose coupled to antiviral interferon antibodies. The results reported here suggest that virus and B-cell stimulants induced interferons which are antigenically related and that T cell-dependent mitogens induce and "interferon like" molecule which appears to be antigenically and physiocochemically different.

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