Acitretin

Excerpt

Acitretin, a member of the retinoid drug class, is the sole FDA-approved systemic retinoid for treating psoriasis, exhibiting efficacy as a standalone therapeutic agent. Retinoids encompass natural and synthetic compounds, similar to vitamin A, and influence various physiological processes. Vitamin A, a vital regulator of the immune system, contributes to cellular growth, differentiation, and proliferation and plays a crucial role in embryonic development. Noteworthy effects of retinoids extend to immunologic anti-inflammatory actions, apoptosis induction, and inhibition of tumor promotion. Beyond its sanctioned use in psoriasis, acitretin finds application in dermatology for off-label purposes. This activity examines the indications, contraindications, and potential adverse events linked to acitretin, empowering interprofessional healthcare team members to manage patients collaboratively and ensure optimal medication utilization in clinical settings.