Use of DNA probes from the 5' flanking region of the HLA-B gene to examine polymorphism at the HLA-B locus
- PMID: 3013813
- DOI: 10.1016/0198-8859(86)90042-x
Use of DNA probes from the 5' flanking region of the HLA-B gene to examine polymorphism at the HLA-B locus
Abstract
Two DNA probes isolated from the region 5' to the HLA-B gene are described. One of these, pCH6, detects a TaqI polymorphism which is correlated with serological alleles of HLA-B. Both probes are used to show a high level of DNA sequence homology between the 5' flanking region of HLA-B and HLA-C.
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