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. 2018 Nov;24(11):2131-2133.
doi: 10.3201/eid2411.181274. Epub 2018 Nov 17.

Molecular Characterization of African Swine Fever Virus, China, 2018

Shengqiang Ge, Jinming Li, Xiaoxu Fan, Fuxiao Liu, Lin Li, Qinghua Wang, Weijie Ren, Jingyue Bao, Chunju Liu, Hua Wang, Yutian Liu, Yongqiang Zhang, Tiangang Xu, Xiaodong Wu, Zhiliang Wang

Molecular Characterization of African Swine Fever Virus, China, 2018

Shengqiang Ge et al. Emerg Infect Dis. 2018 Nov.

Abstract

On August 3, 2018, an outbreak of African swine fever in pigs was reported in China. We subjected a virus from an African swine fever-positive pig sample to phylogenetic analysis. This analysis showed that the causative strain belonged to the p72 genotype II and CD2v serogroup 8.

Keywords: ASF; ASFV; African swine fever; African swine fever virus; China; causative virus strain; genotype; molecular characterization; outbreak; pigs; serotype; viruses; zoonoses.

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Figures

Figure
Figure
Phylogenetic analysis of a causative virus strain (China 2018/1) of an African swine fever outbreak, China, 2018. A) p72 genotype; B) CD2v serogroup. The neighbor-joining method and Kimura 2-parameter model were used for construction of phylogenetic trees in MEGA 5.0 software (https://www.megasoftware.net/). Numbers along branches indicate bootstrap values >70% (1,000 replicates). Black circles indicate causative virus from this study. Roman numerals to the right in panel A indicate p72 genotypes. Numbers to the right in panel B indicate CD2v serogroups. GenBank accession numbers are provided for all sequences. Scale bars indicate nucleotide substitutions per site.
See this image and copyright information in PMC

References

    1. Alonso C, Borca M, Dixon L, Revilla Y, Rodriguez F, Escribano JM; Ictv Report Consortium. ICTV virus taxonomy profile: Asfarviridae. J Gen Virol. 2018;99:613–4. 10.1099/jgv.0.001049 - DOI - PMC - PubMed
    1. Wang Q, Ren W, Bao J, Ge S, Li J, Li L, et al. The first outbreak of African swine fever was confirmed in China [in Chinese]. Journal of China Animal Health Inspection. 2018;35:1–5.
    1. Bastos AD, Penrith ML, Crucière C, Edrich JL, Hutchings G, Roger F, et al. Genotyping field strains of African swine fever virus by partial p72 gene characterisation. Arch Virol. 2003;148:693–706. 10.1007/s00705-002-0946-8 - DOI - PubMed
    1. Sanna G, Dei Giudici S, Bacciu D, Angioi PP, Giammarioli M, De Mia GM, et al. Improved strategy for molecular characterization of African swine fever viruses from Sardinia, based on analysis of p30, CD2V and I73R/I329L variable regions. Transbound Emerg Dis. 2017;64:1280–6. 10.1111/tbed.12504 - DOI - PubMed
    1. Gallardo C, Fernández-Pinero J, Pelayo V, Gazaev I, Markowska-Daniel I, Pridotkas G, et al. Genetic variation among African swine fever genotype II viruses, eastern and central Europe. Emerg Infect Dis. 2014;20:1544–7. 10.3201/eid2009.140554 - DOI - PMC - PubMed

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