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Editorial
. 2018 Aug 24;16(8):e3000009.
doi: 10.1371/journal.pbio.3000009. eCollection 2018 Aug.

The small things can matter

Norman R Pace  1
Affiliations
Editorial

The small things can matter

Norman R Pace. PLoS Biol. .

Abstract

In the context of biology as a whole and of our own personal lives, seemingly small things can prove surprisingly influential. Here, I consider the powerful impact of small organisms-the inhabitants of the microbial world-and the small events that shaped my own development as a scientist. I reflect on the early days of the fields of molecular biology and microbial ecology and my own role in the origin story of what we now call "metagenomics".

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Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Image 1
Image 1. Norman R. Pace.
See this image and copyright information in PMC

References

    1. Pace NR, Sapp J Goldenfeld N. Phylogeny and beyond: Scientific, historical and conceptual significance of the first tree of life. Proc. Natl. Acad. Sci. USA. 2012;109:1011–1018. 10.1073/pnas.1109716109 - DOI - PMC - PubMed
    1. Stahl DA, Lane DJ, Olsen GJ, Pace NR. The analysis of hydrothermal vent-associated symbionts by ribosomal RNA sequences. Science. 1984;224:409–411. www.ncbi.nlm.nih.gov/pubmed/17741220 10.1126/science.224.4647.409 - DOI - PubMed
    1. Stahl DA, Lane DJ, Olsen GJ, Pace NR. Characterization of a Yellowstone hot spring microbial community by 5S ribosomal RNA sequences. Appl. Environ. Microbiol. 1985;49:1379–1384. www.ncbi.nlm.nih.gov/pubmed/2409920 - PMC - PubMed
    1. Lane DJ, Pace B, Olsen GJ, Stahl DA, Sogin ML, Pace NR. Rapid determination of 16S ribosomal RNA sequences for phylogenetic analyses. Proc. Natl. Acad. Sci. USA. 1985;82:6955–6959. www.ncbi.nlm.nih.gov/pubmed/2413450 - PMC - PubMed
    1. DeLong EF, Wickham GS, Pace NR. Phylogenetic stains: ribosomal RNA-based probes for the identification of single cells. Science 1991;243:1360–1363. science.sciencemag.org/content/243/4896/1360 - PubMed

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