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Review
. 2018 Oct;13(5):557-565.
doi: 10.1007/s11523-018-0583-0.

Targeted Therapies in the Treatment of Sarcomas

Brianna Hoffner  1 , Anthony D Elias  2 , Victor M Villalobos  1
Affiliations
Review

Targeted Therapies in the Treatment of Sarcomas

Brianna Hoffner et al. Target Oncol. 2018 Oct.

Abstract

About 50% of sarcomas have specific pathology-defining molecular alterations including mutations, fusion genes, and gene amplifications. Some of these alterations appear to be oncogenic drivers, and a subset can be utilized as targets for standard or experimental molecularly targeted agents in the clinic. In addition, immunotherapies may have a growing role in the treatment of sarcomas in the future.

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