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. 2018 Oct:75:89-91.
doi: 10.1016/j.ijid.2018.08.009. Epub 2018 Aug 23.

A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China

Jie Li  1 , Xiaoyan Lu  2 , Yamin Sun  3 , Changying Lin  1 , Feng Li  3 , Yang Yang  1 , Zhichao Liang  1 , Lei Jia  1 , Lijuan Chen  1 , Baoming Jiang  2 , Quanyi Wang  4
Affiliations

A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China

Jie Li et al. Int J Infect Dis. 2018 Oct.

Abstract

Patients with swimming pool-acquired human adenovirus (HAdV) infections usually manifest characteristic clinical features that include fever, pharyngitis, and conjunctival inflammation, syndromically referred to as pharyngoconjunctival fever (PCF). HAdV types 3, 4, and 7 are most commonly associated with PCF. This article reports an outbreak of PCF that involved 55 students and staff at a university in Beijing, China. Fifty patients had used the same swimming pool 2 weeks before the onset of symptoms. HAdV type 4 was identified from patient eye and throat swabs and concentrated swimming pool water samples. Partial hexon gene sequences obtained from the water samples were 100% identical to the sequences obtained from the swab samples, which clustered with HAdV-4 within species E. Swimming pool water contaminated with HAdV-4 was the most likely source of infection, although one instance of likely person-to-person transmission was noted.

Keywords: Human adenovirus; Outbreak; Pharyngoconjunctival fever.

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Conflict of interest statement

Conflict of interest

No conflict of interest to declare.

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