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Review
. 2018 Sep;45(3):453-466.
doi: 10.1016/j.clp.2018.05.014.

Necrotizing Enterocolitis and Neurodevelopmental Outcome

Affiliations
Review

Necrotizing Enterocolitis and Neurodevelopmental Outcome

Ira Adams-Chapman. Clin Perinatol. 2018 Sep.

Abstract

Necrotizing enterocolitis is a serious complication of prematurity that is associated with an increased risk for adverse neurodevelopmental outcome secondary to a complex relationship between various morbidities that increase the risk for central nervous system injury. Affected infants are exposed to a variety of circulating cytokines known to be associated with white matter injury. These infants also have an increased risk of secondary blood stream infections and nutritional compromise.

Keywords: Follow-up; Necrotizing enterocolitis; Neurodevelopment; Sepsis.

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