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Review
. 2018 Aug 16;15(3):808-811.
doi: 10.1016/j.jor.2018.08.012. eCollection 2018 Sep.

Eosinophilic granuloma of the spine involving C1 and pulmonary infiltration in young children - Presentation of two cases with a follow-up over 10 years including review of the literature

Tugrul Kocak  1 , Benjamin Ulmar  2 , Heiko Reichel  1 , Sebastian Weckbach  1
Affiliations
Review

Eosinophilic granuloma of the spine involving C1 and pulmonary infiltration in young children - Presentation of two cases with a follow-up over 10 years including review of the literature

Tugrul Kocak et al. J Orthop. .

Erratum in

Abstract

Objectives: The incidence of spinal eosinophilic granuloma in children is low.

Methods: Clinical case presentation of two children (♀ 18 months old, ♂ 16 months old) complaining of acute torticollis. Follow-up period was 11 years in the female patient and 13 years in the male patient.

Results: The diagnostics certified a spinal eosinophilic granuloma: the girl had a multilevel spinal disease including the atlas, the boy a thoracic and pulmonary manifestation. Both were treated with chemotherapy with good clinical results.

Conclusions: Overall, the above described is a very rare clinical entity. However, persisting torticollis in children should be clearly diagnosed.

Keywords: Atlas; Chemotherapy; Children; Eosinophilic granuloma; Spine.

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Figures

Fig. 1
Fig. 1
a, b, c. CT scans of the cervical spine of the female patient: Lytic lesions of the left lateral mass of the atlas (C1) and the sixth cervical vertebra (C6).
Fig. 2
Fig. 2
a. MRI of the atlas (C1) of the female patient showed a lytic lesion of the left lateral mass. b. MRI of the female patient showed fluid between the dens axis (C2) and the anterior arch of the atlas (C1). The seventh thoracic vertebra (T7) is shown as a classical vertebra plana.
Fig. 3
Fig. 3
CT of the male patient showing a lytic destruction of the third thoracic vertebra (T3) with involvement of the adjacent soft tissue and osteolysis of the left pedicle. In the scans the pulmonary infiltration in right second segment can also be observed.
Fig. 4
Fig. 4
MRI of the complete spine of the boy with a vertebra plana at the level of the third thoracic vertebra (T3).
Fig. 5
Fig. 5
MRI of the cervical and thoracic spine of the girl with stable situation due to T7. The atlas (C1) and C6 come regularly to the presentation. New, but healed fracture of C3.
Fig. 6
Fig. 6
MRI of the cervical and thoracic spine of the boy with almost complete restoration of the previous concerned T3 vertebra. Pulmonary affection was exluded.
See this image and copyright information in PMC

References

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