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Review
. 2018 Jul 26:2018:7823182.
doi: 10.1155/2018/7823182. eCollection 2018.

The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss

Aruchuna Ruban  1 , Hutan Ashrafian  1 , Julian P Teare  1
Affiliations
Review

The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss

Aruchuna Ruban et al. Gastroenterol Res Pract. .

Abstract

The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice.

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Figures

Figure 1
Figure 1
The EndoBarrier device.
Figure 2
Figure 2
Bile flowing around the outside of the sleeve coming into contact with nutrients distally in the jejunum.
Figure 3
Figure 3
Duodenal sleeve implantation.
See this image and copyright information in PMC

References

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