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Case Reports
. 2018 Jun 22;10(6):e2866.
doi: 10.7759/cureus.2866.

Metastatic Lung Adenocarcinoma Presenting with Hypereosinophilia

Omar Abughanimeh  1 , Mohammad Tahboub  2 , Mouhanna Abu Ghanimeh  3
Affiliations
Case Reports

Metastatic Lung Adenocarcinoma Presenting with Hypereosinophilia

Omar Abughanimeh et al. Cureus. .

Abstract

Lung cancer is one of the most common malignancies in both male and female patients. It is classified into small cell lung cancers and non-small cell lung cancers. Lung adenocarcinoma is a subtype of non-small cell lung cancer and accounts for the highest prevalence of lung cancer. Eosinophils are white blood cells (WBCs) that originate from the granulocytic lineage. Hypereosinophilia is a rare condition characterized by an absolute eosinophil count (AEC) of more than 1500 cells/µL. This is different from eosinophilia, which is defined as an absolute eosinophil count of more than 500 cells/µL. Hypereosinophilia is associated with several conditions, including allergic disorders, helminth infections, rheumatologic disorders, and hematologic malignancies. Paraneoplastic eosinophilia is a rare finding in solid malignancies. Herein, we report the case of a 55-year-old male who presented with shortness of breath and chest pain and whose workup showed metastatic lung adenocarcinoma associated with hypereosinophilia in the absence of a primary bone marrow disorder.

Keywords: eosinophilia; hypereosinophilia; metastatic lung adenocarcinoma.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. A CT pulmonary angiogram showing a 3.6-cm speculated mass within the anterior right upper lobe
CT: computed tomography
Figure 2
Figure 2. WBCs and eosinophils trend during admission
See this image and copyright information in PMC

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