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Review
. 2018 Jul 26:2018:4721357.
doi: 10.1155/2018/4721357. eCollection 2018.

Management of Hypertriglyceridemia Induced Acute Pancreatitis

Rajat Garg  1 , Tarun Rustagi  2
Affiliations
Review

Management of Hypertriglyceridemia Induced Acute Pancreatitis

Rajat Garg et al. Biomed Res Int. .

Abstract

Hypertriglyceridemia is an uncommon but a well-established etiology of acute pancreatitis leading to significant morbidity and mortality. The risk and severity of acute pancreatitis increase with increasing levels of serum triglycerides. It is crucial to identify hypertriglyceridemia as the cause of pancreatitis and initiate appropriate treatment plan. Initial supportive treatment is similar to management of other causes of acute pancreatitis with additional specific therapies tailored to lower serum triglycerides levels. This includes plasmapheresis, insulin, heparin infusion, and hemofiltration. After the acute episode, diet and lifestyle modifications along with hypolipidemic drugs should be initiated to prevent further episodes. Currently, there is paucity of studies directly comparing different modalities. This article provides a comprehensive review of management of hypertriglyceridemia induced acute pancreatitis. We conclude by summarizing our treatment approach to manage hypertriglyceridemia induced acute pancreatitis.

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Figures

Figure 1
Figure 1
Proposed algorithm for treatment of HTG-AP.
See this image and copyright information in PMC

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