Use of time-varying coefficients in a Cox regression model when the proportional hazard assumption is violated

Maofeng Wang¹, Weimin Li², Nadir Yehya³, Garrett Keim³, Neal J Thomas⁴

Affiliations

¹ Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, 322100, Zhejiang, People's Republic of China.
² Department of Cardiology, Affiliated Dongyang Hospital of Wenzhou Medical University, 60 Wuning West Road, Dongyang, 322100, Zhejiang, People's Republic of China. dyliwm@126.com.
³ Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, 6040A Wood Building, 3401 Civic Center Boulevard, Philadelphia, PA, 19104, USA.
⁴ Department of Pediatrics and Public Health Science, Division of Pediatric Critical Care Medicine, Penn State Hershey Children's Hospital, 500 University Drive, Hershey, PA, 17033, USA.

PMID: 30151689
DOI: 10.1007/s00134-018-5351-1

Comment

Use of time-varying coefficients in a Cox regression model when the proportional hazard assumption is violated

Maofeng Wang et al. Intensive Care Med. 2018 Nov.

. 2018 Nov;44(11):2017-2019.

doi: 10.1007/s00134-018-5351-1. Epub 2018 Aug 27.

Authors

Maofeng Wang¹, Weimin Li², Nadir Yehya³, Garrett Keim³, Neal J Thomas⁴

Affiliations

¹ Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, 322100, Zhejiang, People's Republic of China.
² Department of Cardiology, Affiliated Dongyang Hospital of Wenzhou Medical University, 60 Wuning West Road, Dongyang, 322100, Zhejiang, People's Republic of China. dyliwm@126.com.
³ Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, 6040A Wood Building, 3401 Civic Center Boulevard, Philadelphia, PA, 19104, USA.
⁴ Department of Pediatrics and Public Health Science, Division of Pediatric Critical Care Medicine, Penn State Hershey Children's Hospital, 500 University Drive, Hershey, PA, 17033, USA.

PMID: 30151689
DOI: 10.1007/s00134-018-5351-1

No abstract available

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Comment on

Subtypes of pediatric acute respiratory distress syndrome have different predictors of mortality.
Yehya N, Keim G, Thomas NJ. Yehya N, et al. Intensive Care Med. 2018 Aug;44(8):1230-1239. doi: 10.1007/s00134-018-5286-6. Epub 2018 Jul 3. Intensive Care Med. 2018. PMID: 29971591 Free PMC article.

Cited by

'Lumping or splitting' in paediatric acute respiratory distress syndrome (PARDS).
De Luca D, Harrison DA, Peters MJ. De Luca D, et al. Intensive Care Med. 2018 Sep;44(9):1548-1550. doi: 10.1007/s00134-018-5323-5. Epub 2018 Aug 24. Intensive Care Med. 2018. PMID: 30143835 No abstract available.

References

1. Lancet Respir Med. 2014 Aug;2(8):611-20 - PubMed
1. Ann Transl Med. 2017 Feb;5(3):47 - PubMed
1. Ann Transl Med. 2018 Apr;6(7):121 - PubMed

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Use of time-varying coefficients in a Cox regression model when the proportional hazard assumption is violated

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Use of time-varying coefficients in a Cox regression model when the proportional hazard assumption is violated

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