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Multicenter Study
. 2018 Dec;29(8):877-880.
doi: 10.1111/pai.12977. Epub 2018 Nov 13.

Circulating 25-hydroxyvitamin D, nasopharyngeal microbiota, and bronchiolitis severity

Laura Toivonen  1   2 , Kohei Hasegawa  1 , Nadim J Ajami  3 , Juan C Celedón  4 , Jonathan M Mansbach  5 , Joseph F Petrosino  3 , Carlos A Camargo Jr  1
Affiliations
Multicenter Study

Circulating 25-hydroxyvitamin D, nasopharyngeal microbiota, and bronchiolitis severity

Laura Toivonen et al. Pediatr Allergy Immunol. 2018 Dec.
No abstract available

Keywords: airway microbiota; children; infant; microbiome; respiratory infection; vitamin D.

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Conflict of interest statement

Conflicts of interest:The authors have no conflicts of interest relevant to this article to disclose.

Figures

Figure 1.
Figure 1.. Associations between nasopharyngeal microbiota profiles and risk of intensive care use in infants hospitalized for bronchiolitis by serum total 25-hydroxyvitamin D (25OHD) status
Random-effects model accounting for patient clustering at the hospital-level and adjusting for 12 factors (age, sex, race/ethnicity, gestational age, siblings at home, breastfeeding, history of breathing problems, lifetime history of systemic antibiotic use, weight at hospitalization, serum LL-37 level, and virology [RSV, rhinovirus]) was constructed for each strata – i.e., infants below or above the median serum total 25OHD levels (26.5 ng/ml). Moraxella-dominant profile was used as the reference. Full models are presented in Table E3.
See this image and copyright information in PMC

References

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