Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016

Abstract

Objectives: Up-to-date information on the patterns of acute poisoning is crucial for the proper management of poisoning events. The objectives of this study were to analyse the characteristics of patients suffering from acute poisoning admitted to the emergency department (ED) in a tertiary medical centre in Northeast China and to compare these characteristics with those of a previous comparable study.

Design: Retrospective and descriptive study.

Setting: Data were collected from the hospital information system in Shengjing Hospital, China, from January 2012 to December 2016.

Participants: All cases aged ≥11 years old with a diagnosis of acute poisoning.

Results: In total, 5009 patients aged ≥11 years presented to the ED with acute poisoning during the study period. The average age of the patients was 36.0±15.1 years and over half (52.7%) were in the 20-39age group. The female to male ratio was 1.2:1. Patients with acute poisoning mainly lived in rural areas rather than in urban areas. The majority of patients consumed poison as suicide attempts (56.7%). Men were more commonly poisoned by drug abuse than women, but women outnumbered men in suicidal poisoning. The most common form of poison intake was ingestion (oral intake; 86.2%). The five most common toxic agent groups, in descending order, were therapeutic drugs (32.6%), pesticides (26.9%), alcohol (20.7%), fumes/gases/vapours (11.4%) and chemicals (3.6%). Sedatives/hypnotics in the therapeutic drugs group and paraquat in the pesticides group were the most common toxic agents, respectively. The mortality rate of study participants was 1.3%, with 64 deaths.

Conclusions: The results of this study indicate the need to strengthen education on the rational and safe use of drugs in Shenyang.

Keywords: carbon monoxide poisoning; paraquat; pesticides; poisoning; suicide.

Figure 1

Distribution of all poisoning cases by age and gender.

Figure 2

Intention for the 20–29 age group cases from 2012 to 2016.

Figure 3

Distribution of therapeutic drugs poisoning by age and gender.

Figure 4

Distribution of pesticide poisoning by age and gender.

Figure 5

Distribution of alcohol and fumes poisoning by age and gender. A-Male means alcohol poisoning for male; A-Female means alcohol poisoning for female; F-Male means fumes/gas/fog poisoning for male; and F-Female means fumes/gas/fog poisoning for female.