Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 May-Aug;22(2):161-162.
doi: 10.4103/jomfp.JOMFP_79_18.

Splendore-Hoeppli phenomenon

Divya Gopinath  1
Affiliations

Splendore-Hoeppli phenomenon

Divya Gopinath. J Oral Maxillofac Pathol. 2018 May-Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Histological features of Splendore–Hoeppli phenomenon appearing as strongly eosinophilic amorphous material with star-like (asteroid) configuration
Figure 2
Figure 2
Splendore–Hoeppli phenomenon amid granulomatous reaction composed of histiocytes and inflammatory cells and occasional giant cells
Figure 3
Figure 3
Hand-drawn illustration of the mechanism of Splendore–Hoeppli phenomenon representing fungal hyphae surrounded deposition of antigen–antibody complexes, glycoprotein and debris from host inflammatory cells
See this image and copyright information in PMC

References

    1. Kwangsukstith C, Vanittanakom N, Khanjanasthiti P, Uthammachai C. Cutaneous sporotrichosis in Thailand: First reported case. Mycoses. 1990;33:513–7. - PubMed
    1. Liber AF, Choi HS. Splendore-Hoeppli phenomenon about silk sutures in tissue. Arch Pathol. 1973;95:217–20. - PubMed
    1. Hussein MR. Mucocutaneous Splendore-Hoeppli phenomenon. J Cutan Pathol. 2008;35:979–88. - PubMed
    1. Smith JH, Von Lichtenberg F. The Hoeppli phenomenon in schistosomiasis. II. Histochemistry. Am J Pathol. 1967;50:993–1007. - PMC - PubMed
    1. Miller RI, Campbell RS. The comparative pathology of equine cutaneous phycomycosis. Vet Pathol. 1984;21:325–32. - PubMed