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Case Reports
. 2018 Aug 8:2018:8125096.
doi: 10.1155/2018/8125096. eCollection 2018.

Recurrence of Cryptococcal Meningitis and the Hidden Role of Patient Education and Social Support

Affiliations
Case Reports

Recurrence of Cryptococcal Meningitis and the Hidden Role of Patient Education and Social Support

Felix Bongomin et al. Case Rep Neurol Med. .

Abstract

Human immunodeficiency virus- (HIV-) associated cryptococcal meningitis (CM) is one of the leading causes of deaths among patients living with HIV/AIDS in resource-limited settings, accounting for ~15-20% of AIDS-related deaths globally. We present our experience with a 25-year-old woman living with HIV who had a recurrent cryptococcal disease due to nonadherence to HIV care and lack of awareness of the benefits of adherence to secondary prophylaxis for CM. This case highlights the fact that fungal diseases awareness should not be limited only to the health professionals and public health practitioners, but also to patients, caregivers, and stakeholders.

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Figures

Figure 1
Figure 1
India ink preparation demonstrating numerous budding yeast cells surrounded by capsular halo consistent with the identification of Cryptococcus species. X100.
Figure 2
Figure 2
A map of Uganda showing the patient's hometown and the two regional referral hospitals where she could access HIV and cryptococcal meningitis care from.

References

    1. Sloan D. J., Parris V. Cryptococcal meningitis: epidemiology and therapeutic options. Journal of Clinical Epidemiology. 2014;6(1):169–182. doi: 10.2147/CLEP.S38850. - DOI - PMC - PubMed
    1. Rajasingham R., Smith R. M., Park B. J., et al. Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis. The Lancet Infectious Diseases. 2017;17(8):873–881. doi: 10.1016/S1473-3099(17)30243-8. - DOI - PMC - PubMed
    1. Jarvis J. N., Harrison T. S. HIV-associated cryptococcal meningitis. AIDS. 2007;21(16):2119–2129. doi: 10.1097/qad.0b013e3282a4a64d. - DOI - PubMed
    1. Perfect J. R., Dismukes W. E., Dromer F., et al. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of America. Clinical Infectious Diseases. 2010;50(3):291–322. doi: 10.1086/649858. - DOI - PMC - PubMed
    1. Day J. N., Chau T. T. H., Wolbers M., et al. Combination antifungal therapy for cryptococcal meningitis. The New England Journal of Medicine. 2013;368(14):1291–1302. doi: 10.1056/NEJMoa1110404. - DOI - PMC - PubMed

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