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Review
. 2018 Feb 1;3(1):29-38.
doi: 10.1016/j.ncrna.2018.01.001. eCollection 2018 Mar.

Carcinogenesis in prostate cancer: The role of long non-coding RNAs

John Aird  1 , Anne-Marie Baird  1   2   3   4 , Marvin C J Lim  1   5   6 , Ray McDermott  5   6 , Stephen P Finn  1   3 , Steven G Gray  3   7   8   9
Affiliations
Review

Carcinogenesis in prostate cancer: The role of long non-coding RNAs

John Aird et al. Noncoding RNA Res. .

Erratum in

Abstract

LncRNAs appear to play a considerable role in tumourigenesis through regulating key processes in cancer cells such as proliferative signalling, replicative immortality, invasion and metastasis, evasion of growth suppressors, induction of angiogenesis and resistance to apoptosis. LncRNAs have been reported to play a role in prostate cancer, particularly in regulating the androgen receptor signalling pathway. In this review article, we summarise the role of 34 lncRNAs in prostate cancer with a particular focus on their role in the androgen receptor signalling pathway and the epithelial to mesenchymal transition pathway.

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Figures

Fig. 1
Fig. 1
lncRNAs that have been shown to interact with the Androgen Receptor (AR).
Fig. 2
Fig. 2
lncRNA associated with EMT and Prostate Cancer.
See this image and copyright information in PMC

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