[Radiologically isolated syndrome as a possible preclinical stage of primary-progressive multiple sclerosis]
- PMID: 30160666
- DOI: 10.17116/jnevro201811808235
[Radiologically isolated syndrome as a possible preclinical stage of primary-progressive multiple sclerosis]
Abstract
The article presents a clinical case-report of transformation of radiologically isolated syndrome (RIS) to primary-progressive multiple sclerosis (PPMS). It also provides a review of international and Russian data on the comparison of clinical and MRI characteristics of PPMS with relapsing-remitting multiple sclerosis and secondary-progressive multiple sclerosis and the review of the current data on the risks of transition of RIS to PPMS.
Представлены клинический случай трансформации радиологически изолированного синдрома (РИС) в первично-прогрессирующий рассеянный склероз (ППРС), а также обзор международных и российских данных по особенностям клинических и МРТ-проявлений ППРС в сравнении с ремиттирующим рассеянным склерозом и вторично-прогрессирующим рассеянным склерозом. Представлен обзор современных данных по рискам перехода РИС в ППРС.
Keywords: multiple sclerosis; primary-progressive multiple sclerosis; prognosis; radiologically isolated syndrome.
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