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Case Reports
. 2018;118(8. Vyp. 2):35-39.
doi: 10.17116/jnevro201811808235.

[Radiologically isolated syndrome as a possible preclinical stage of primary-progressive multiple sclerosis]

[Article in Russian]
E V Popova  1 , V V Bryukhov  2 , A N Boyko  1 , M V Krotenkova  2
Affiliations
Case Reports

[Radiologically isolated syndrome as a possible preclinical stage of primary-progressive multiple sclerosis]

[Article in Russian]
E V Popova et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2018.

Abstract
in English, Russian

The article presents a clinical case-report of transformation of radiologically isolated syndrome (RIS) to primary-progressive multiple sclerosis (PPMS). It also provides a review of international and Russian data on the comparison of clinical and MRI characteristics of PPMS with relapsing-remitting multiple sclerosis and secondary-progressive multiple sclerosis and the review of the current data on the risks of transition of RIS to PPMS.

Представлены клинический случай трансформации радиологически изолированного синдрома (РИС) в первично-прогрессирующий рассеянный склероз (ППРС), а также обзор международных и российских данных по особенностям клинических и МРТ-проявлений ППРС в сравнении с ремиттирующим рассеянным склерозом и вторично-прогрессирующим рассеянным склерозом. Представлен обзор современных данных по рискам перехода РИС в ППРС.

Keywords: multiple sclerosis; primary-progressive multiple sclerosis; prognosis; radiologically isolated syndrome.

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