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. 1985 Oct;5(10):2832-5.
doi: 10.1128/mcb.5.10.2832-2835.1985.

Murine leukemia virus long terminal repeat sequences can enhance gene activity in a cell-type-specific manner

F K Yoshimura, B Davison, K Chaffin

Murine leukemia virus long terminal repeat sequences can enhance gene activity in a cell-type-specific manner

F K Yoshimura et al. Mol Cell Biol. 1985 Oct.

Abstract

We tested the ability of sequences in the long terminal repeat (LTR) of a mink cell focus-forming (MCF) murine leukemia virus to function as an enhancer in a cell-type-specific manner. In a stable transformation assay, the MCF or Akv LTR and the simian virus 40 enhancer had similar activities in murine fibroblasts. In contrast, the MCF LTR had a significantly greater activity in murine T lymphoid cells than did either the simian virus 40 enhancer or the Akv LTR.

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