CD4:CD8 ratio and CD8+ cell count for prognosticating mortality in HIV-infected patients on antiretroviral therapy
- PMID: 30167571
- PMCID: PMC6112816
- DOI: 10.21037/jlpm.2018.01.10
CD4:CD8 ratio and CD8+ cell count for prognosticating mortality in HIV-infected patients on antiretroviral therapy
Conflict of interest statement
Conflicts of Interest: The authors have no conflicts of interest to declare.
Comment on
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CD4:CD8 Ratio and CD8 Count as Prognostic Markers for Mortality in Human Immunodeficiency Virus-Infected Patients on Antiretroviral Therapy: The Antiretroviral Therapy Cohort Collaboration (ART-CC).Clin Infect Dis. 2017 Sep 15;65(6):959-966. doi: 10.1093/cid/cix466. Clin Infect Dis. 2017. PMID: 28903507 Free PMC article.
References
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- Margolick JB, Muñoz A, Donnenberg AD, et al. Failure of T-cell homeostasis preceding AIDS in HIV-1 infection. The Multicenter AIDS Cohort Study. Nat Med 1995;1:674–80. - PubMed
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- Kolber MA, Saenz MO, Tanner TJ, et al. Intensification of a suppressive HAART regimen increases CD4 counts and decreases CD8+ T-cell activation. Clin Immunol 2008;126:315–21. - PubMed
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