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. 1986;51(1):47-8.
doi: 10.1111/j.1423-0410.1986.tb00207.x.

Effect of beta-propiolactone on blood group antibody detection

A F Hunt, M T Jones, G J Howkins

Effect of beta-propiolactone on blood group antibody detection

A F Hunt et al. Vox Sang. 1986.

Abstract

A panel of 50 blood group antibodies covering a range of blood group antigens has been tested in the presence of 0.25% beta-propiolactone as a possible means of reducing infectivity of high-risk HTLV III/HBsAg samples. 11/50 (22%) antibodies could not be detected by the indirect antiglobulin test, and 6/40 (15%) were undetectable by the two-stage papain technique.

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