Enhancement of gamma-aminobutyric acid receptor binding by protopine-type alkaloids
- PMID: 3017370
Enhancement of gamma-aminobutyric acid receptor binding by protopine-type alkaloids
Abstract
Protopine, cryptopine and allocryptopine were demonstrated to enhance 3H-gamma-aminobutyric acid (3H-GABA) binding to rat brain synaptic membrane receptors. The above finding might be indicative of benzodiazepine-like activity of these alkaloids.