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. 1986 Jun;36(6):939-40.

Enhancement of gamma-aminobutyric acid receptor binding by protopine-type alkaloids

  • PMID: 3017370

Enhancement of gamma-aminobutyric acid receptor binding by protopine-type alkaloids

J Kardos et al. Arzneimittelforschung. 1986 Jun.

Abstract

Protopine, cryptopine and allocryptopine were demonstrated to enhance 3H-gamma-aminobutyric acid (3H-GABA) binding to rat brain synaptic membrane receptors. The above finding might be indicative of benzodiazepine-like activity of these alkaloids.

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