Pulmonary disorders that are potentially associated with anti- neutrophilic cytoplasmic antibodies: A brief review

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis frequently manifests with involvement of the lungs and kidneys, and it also may affect other anatomic sites. This article presents the patterns of pulmonary injury in which ANCA-associated vasculitis is included in the differential diagnosis, with a discussion of antineutrophil cytoplasmic antibody testing methods. The histologic features of non-vasculitic, potentially-ANCA-associated pulmonary lesions are reviewed briefly as well.

Keywords: Antineutrophic cytoplasmic antibodies; Eosinophilic granulomatosis-polyangiitis; Granulomatosis-polyangiitis; Microscopic polyangiitis; Vasculitis.