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. 2018 Aug 21:14:2133-2140.
doi: 10.2147/NDT.S174293. eCollection 2018.

Chinese version of Montreal Cognitive Assessment Basic for discrimination among different severities of Alzheimer's disease

Lin Huang  1 , Ke-Liang Chen  1 , Bi-Ying Lin  1 , Le Tang  1 , Qian-Hua Zhao  1 , Ying-Ru Lv  2 , Qi-Hao Guo  1
Affiliations

Chinese version of Montreal Cognitive Assessment Basic for discrimination among different severities of Alzheimer's disease

Lin Huang et al. Neuropsychiatr Dis Treat. .

Abstract

Objectives: To find out whether the Chinese version of Montreal Cognitive Assessment Basic (MoCA-BC) and its subtests could be applied in discrimination among cognitively normal controls (NC), mild cognitive impairment (MCI), mild and moderate Alzheimer's Disease (AD), and furthermore, to determine the optimal cutoffs most sensitive to distinguish between them.

Design: A cross-sectional validation study.

Setting: Huashan Hospital, Shanghai, China.

Participants: There was a total of 1,969 participants: individuals with MCI (n=663), mild (n=345), moderate (n=441) AD, and cognitively NC (n=520) were recruited from the Memory Clinic, Huashan Hospital, Shanghai, China.

Measurements: Baseline MoCA-BC scores were collected from firsthand data. Two subtests were calculated from MoCA-BC: the Memory Index Score of MoCA-BC (MoCA-BC-MIS) and the Non-memory Index Score of MoCA-BC (MoCA-BC-NM).

Results: MoCA-BC was an effective cognitive tool to discriminate among NC, MCI, mild and moderate AD in the Chinese elderly across all education groups, implying that it was efficient not only for detecting MCI, but for different severities of AD as well. For MCI screening, the total score of MoCA-BC (MoCA-BC-T) and MoCA-BC-MIS had similar high sensitivity and specificity. For discrimination among MCI, mild and moderate AD, the MoCA-BC-T and MoCA-BC-NM had similar performance.

Conclusion: MoCA-BC is an effective cognitive test to distinguish between NC, MCI, mild and moderate AD among the Chinese elderly with various levels of education.

Keywords: Alzheimer’s disease; Montreal Cognitive Assessment; cutoff study; mild cognitive impairment.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

References

    1. Freitas S, Simões MR, Alves L, Santana I. Montreal cognitive assessment: validation study for mild cognitive impairment and Alzheimer disease. Alzheimer Dis Assoc Disord. 2013;27(1):37–43. - PubMed
    1. Freitas S, Simões MR, Alves L, Santana I. Montreal Cognitive Assessment: influence of sociodemographic and health variables. Arch Clin Neuropsychol. 2012;27(2):165–175. - PubMed
    1. Lu J, Li D, Li F, et al. Montreal cognitive assessment in detecting cognitive impairment in Chinese elderly individuals: a population-based study. J Geriatr Psychiatry Neurol. 2011;24(4):184–190. - PubMed
    1. Nasreddine ZS, Phillips NA, Bédirian V, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53(4):695–699. - PubMed
    1. Julayanont P, Tangwongchai S, Hemrungrojn S, et al. The Montreal Cognitive Assessment-Basic: A Screening Tool for Mild Cognitive Impairment in Illiterate and Low-Educated Elderly Adults. J Am Geriatr Soc. 2015;63(12):2550–2554. - PubMed

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