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. 2018 Jul;10(7):4230-4235.
doi: 10.21037/jtd.2018.06.18.

Sternal resection and reconstruction for secondary malignancies

Wojciech Dudek  1 , Waldemar Schreiner  1 , Raymund E Horch  2 , Horia Sirbu  1
Affiliations

Sternal resection and reconstruction for secondary malignancies

Wojciech Dudek et al. J Thorac Dis. 2018 Jul.

Abstract

Background: Limited data on sternal and/or anterior chest wall resections for secondary malignancies exist. The purpose of this study was to examine the perioperative outcomes and postoperative overall survival (OS) in patients who underwent sternal and/or anterior chest wall resections for secondary sternal tumors (SSTs).

Methods: A retrospective analysis of all patients who underwent resection of SSTs at single institution between 2000 and 2016 has been performed. OS was estimated using the Kaplan-Meier method.

Results: Ten patients underwent sternal and/or anterior chest wall resection for SSTs with curative (70%) or palliative (30%) intent. Two (20%) patients underwent complete and 8 (80%) partial sternal and/or anterior chest wall resection. There were no perioperative deaths, major complications occurred in 3 (30%) patients. Tumor resection was complete (R0) in 5 (50%) patients. The 5-year OS rate was 40%. No OS difference in R0 vs. R1 resections was observed.

Conclusions: Sternal and/or anterior chest wall resections for SSTs can be performed with low morbidity and mortality. Complete SST resection does not assure favorable OS. Sternal resections can be considered palliative treatment option in patients with stable stage IV disease with isolated sternal involvement.

Keywords: Sternal metastases; chest wall; sternal resection and reconstruction.

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Conflict of interest statement

Conflict of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Coronal (A) and lateral (B) chest CT images in patient #8. CT, computed tomography.
Figure 2
Figure 2
Rectus abdominis myocutaneous pedicled flap.
Figure 3
Figure 3
Aesthetic long-term outcome after partial sternectomy with TRAM reconstruction in patient #8. TRAM, transverse rectus abdominis myocutaneous flap.
Figure 4
Figure 4
Postoperative overall survival.
See this image and copyright information in PMC

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